在劇中出演Michael（張穎康飾）妹妹兼高安（黃浩然飾）大妹及高靖（朱晨麗飾）姐姐的Emma（張曦雯飾）終於在結局篇登場，一出場更被懷疑是情婦及殺人兇手，之後在眾人幫助下洗脫嫌疑。在親兄妹相認之際，同時卻有多人被捲入謀殺案。
嘉美（陳敏之飾）的出現揭開了一宗10年前在三藩市發生的兇案，與袁氏夫婦被殺案極為相似。不過嘉美因為家中接連出現異象而精神萎靡，而高安出席由徐意（湯洛雯飾）及嘉美主持的節目，在與嘉美接觸後有意想不到的發現。
其後Emma與李秋（謝雪心飾）、淑娟（羅蘭飾）及淑娟女兒清秀（李綺雯飾）一同籌辦婚紗騷。由於淑娟在婚紗秀綵排表現未盡人意，清秀對淑娟大發雷霆，Emma挺身維護，與清秀爭執並被清秀誤傷。不久，清秀竟被發現陳屍試身室內，死狀形同袁太，更駭人的是，李秋竟一同遇害。與李秋感情深厚的Dr.Man（李施嬅飾），不得不強忍悲痛為秋姐解剖屍體。
Michael得知婚紗秀發生命案，體貼安慰Emma後，卻見Emma的車尾箱驚現殺人兇刀。之後Emma突然到警署自首，帶同證據並供出行兇動機及過程。不過高安不相信Emma會是殺人兇手，認為當中另有內情。在羈留室內，Emma憶起與Michael最後的對話，不禁黯然落淚。Michael亦為了Emma，決定離開香港。高安從徐意身上得到啟發，洞悉案情疑點，成功證明Emma清白，肯定真兇另有其人。及後，高安來到Emma家中，竟發現高靖倒臥於血泊之中。
來源：《法證先鋒IV》
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